| Host: | Mouse |
| Applications: | FC |
| Reactivity: | Human/Rhesus |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal anti-CD16 for use in FC in Human and Rhesus samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | 3G8 |
| Conjugation: | FITC |
| Isotype: | IgG1k |
| Formulation: | PBS with 4mg/ml BSA and 0.1% sodium azide |
| Storage Instruction: | Store at 2-8°C for up to 1-year, upon receipt. |
| Immunogen: | Human CD16 |
| Background | CD16 (FCGR3A) is a 50-65 kDa cell surface molecule that exists in two forms-a transmembranous form expressed by NK cells and some T cells, and a phosphatidylinositol linked form expressed by granulocytes. CD16 is a low affinity receptor for IgG (FcR III) , and is an important receptor mediating ADCC by NK cells. Human CD16 is expressed in two forms – FCGR3A and FCGR3B. FCGR3A is associated with the FcepsilonRI-gamma subunit and is responsible for antibody-dependent NK cell cytotoxicity. |
Information sourced from Uniprot.org
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