Host: |
Mouse |
Applications: |
FC |
Reactivity: |
Human/Rhesus |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Mouse monoclonal antibody anti-CD16 is suitable for use in Flow Cytometry research applications. |
Clonality: |
Monoclonal |
Clone ID: |
3G8 |
Conjugation: |
FITC |
Isotype: |
IgG1k |
Formulation: |
PBS with 4mg/ml BSA and 0.1% sodium azide |
Storage Instruction: |
Store at 2-8°C upon receipt. |
Background | CD16 (FCGR3A) is a 50-65 kDa cell surface molecule that exists in two forms-a transmembranous form expressed by NK cells and some T cells, and a phosphatidylinositol linked form expressed by granulocytes. CD16 is a low affinity receptor for IgG (FcR III) , and is an important receptor mediating ADCC by NK cells. Human CD16 is expressed in two forms – FCGR3A and FCGR3B. FCGR3A is associated with the FcepsilonRI-gamma subunit and is responsible for antibody-dependent NK cell cytotoxicity. |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance