Host: | Mouse |
Applications: | IHC-P |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Mouse monoclonal antibody anti-CD16 is suitable for use in Immunohistochemistry research applications. |
Clonality : | Monoclonal |
Clone ID : | 2H7 |
Conjugation: | Unconjugated |
Isotype: | IgG2a |
Formulation: | Tissue culture supernatant with sodium azide |
Concentration: | >=18 mg/L |
Dilution Range: | IHC-P 1:80 |
Storage Instruction: | Store at 2-8°C upon receipt. |
Immunogen: | Prokaryotic recombinant protein corresponding to the external domain of the CD16 molecule, common to both the transmembrane form and the GPI-linked form. |
Background | CD16 antigen has a molecular weight of 50 to 70 kD and is a low affinity Fc receptor for complexed IgG, Fc/gamma RIII, expressed on natural killer (NK) cells, granulocytes, activated macrophages and a subset of T cells expressing alpha-beta or gamma-delta T cell antigen receptors. The CD16 antigen exists both as a glycosyl-phosphatidylinositol (GPI)-anchored protein in polymorphonuclear cells and as a transmembrane protein in NK cells. |
Information sourced from Uniprot.org