| Host: | Mouse | 
| Applications: | IHC-P | 
| Reactivity: | Human | 
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. | 
| Short Description : | Mouse monoclonal antibody anti-CD16 is suitable for use in Immunohistochemistry research applications. | 
| Clonality : | Monoclonal | 
| Clone ID : | 2H7 | 
| Conjugation: | Unconjugated | 
| Isotype: | IgG2a | 
| Formulation: | Tissue culture supernatant with sodium azide | 
| Concentration: | >=18 mg/L | 
| Dilution Range: | IHC-P 1:80 | 
| Storage Instruction: | Store at 2-8°C upon receipt. | 
| Immunogen: | Prokaryotic recombinant protein corresponding to the external domain of the CD16 molecule, common to both the transmembrane form and the GPI-linked form. | 
| Background | CD16 antigen has a molecular weight of 50 to 70 kD and is a low affinity Fc receptor for complexed IgG, Fc/gamma RIII, expressed on natural killer (NK) cells, granulocytes, activated macrophages and a subset of T cells expressing alpha-beta or gamma-delta T cell antigen receptors. The CD16 antigen exists both as a glycosyl-phosphatidylinositol (GPI)-anchored protein in polymorphonuclear cells and as a transmembrane protein in NK cells. | 
Information sourced from Uniprot.org
 
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