Anti-CD158k/KIR3DL2 antibody [SAA0064] {APC} (STJA0029438)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationAPC
IsotypeIgG1k
General Information
| Short Description | Mouse monoclonal Killer Cell Immunoglobulin-Like Receptor 3dl2 antibody for use in FC in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FC |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA0064 |
| Isotype | IgG1k |
| Conjugation | APC |
| Concentration | 0.5 mg/mL |
| Purification | Purified |
| Formulation | PBS pH 7.4, 50% glycerol, 0.05% proclin300 |
| Storage Instruction | Store at 4°C for 12 months. Protect from light. Do not freeze. |
Target Information
| Gene Symbol | KIR3DL2 |
| Gene ID | 3812 |
| Uniprot ID | KI3L2_HUMAN |
Additional Info
| Function | Receptor on natural killer (NK) cells and T cells for MHC class I molecules. Upon binding of peptide-free HLA-F open conformer, negatively regulates NK and T cell effector functions. Acts as a receptor on astrocytes for HLA-F. Through interaction with HLA-F, may protect motor neurons from astrocyte-induced toxicity. |
| Protein Name | Killer Cell Immunoglobulin-Like Receptor 3dl2Cd158 Antigen-Like Family Member KNatural Killer-Associated Transcript 4Nkat-4P70 Natural Killer Cell Receptor Clone Cl-5P70 Nk Receptor Cl-5Cd Antigen Cd158k |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Killer Cell Immunoglobulin-Like Receptor 3dl2 antibodyAnti-Cd158 Antigen-Like Family Member K antibodyAnti-Natural Killer-Associated Transcript 4 antibodyAnti-Nkat-4 antibodyAnti-P70 Natural Killer Cell Receptor Clone Cl-5 antibodyAnti-P70 Nk Receptor Cl-5 antibodyAnti-Cd Antigen Cd158k antibodyAnti-KIR3DL2 antibodyAnti-CD158K antibodyAnti-NKAT4 antibody |
Information sourced from Uniprot.org