CD15 antibody immunohistochemistry paraffin-embedded spleen tissue STJA0033394

Anti-CD15 antibody [MMA] (STJA0033394)

SKU:
STJA0033394
£214.50 - £308.50
Free Shipping
Processing The item has been added
Enquire For Bulk Order

Covered by St John's Laboratory Guarantee

Short Description :Mouse monoclonal anti-CD15 for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:IHC-P
Host:Mouse
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :MMA
Isotype:IgG
Conjugation:Unconjugated
Purification:Affinity Purified
Dilution Range:IHC 1:100-1:200
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Storage Instruction:Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol:FUT4
Gene ID:2526
Uniprot ID:FUT4_HUMAN
Immunogen:A synthesized peptide derived from human FUT4
Tissue Specificity Isoform Short: Expressed at low levels in bone marrow-derived mesenchymal stem cells. Expressed in cord blood immature promyelocytes and in peripheral blood myeloid and lymphoid cell populations.
Function Isoform Short: Catalyzes alpha(1->3) linkage of fucosyl moiety transferred from GDP-beta-L-fucose to N-acetyl glucosamine (GlcNAc) within type 2 lactosamine (LacNAc, Gal-beta(1->4)GlcNAc) glycan attached to N- or O-linked glycoproteins. Robustly fucosylates nonsialylated distal LacNAc unit of the polylactosamine chain to form Lewis X antigen (CD15), a glycan determinant known to mediate important cellular functions in development and immunity. Fucosylates with lower efficiency sialylated LacNAc acceptors to form sialyl Lewis X and 6-sulfo sialyl Lewis X determinants that serve as recognition epitopes for C-type lectins. Together with FUT7 contributes to SELE, SELL and SELP selectin ligand biosynthesis and selectin-dependent lymphocyte homing, leukocyte migration and blood leukocyte homeostasis. In a cell type specific manner, may also fucosylate the internal LacNAc unit of the polylactosamine chain to form VIM-2 antigen that serves as recognition epitope for SELE. Isoform Long: Does not generate Lewis X antigens.
Protein Name Alpha-(1 -3-Fucosyltransferase 4
4-Galactosyl-N-Acetylglucosaminide 3-Alpha-L-Fucosyltransferase
Elam-1 Ligand Fucosyltransferase
Fucosyltransferase 4
Fucosyltransferase Iv
Fuc-Tiv
Fuct-Iv
Galactoside 3-L-Fucosyltransferase
Database Links Reactome: R-HSA-9037629
Cellular Localisation Golgi Apparatus
Golgi Stack Membrane
Single-Pass Type Ii Membrane Protein
Membrane-Bound Form In Trans Cisternae Of Golgi
Alternative Antibody Names Anti-Alpha-(1 -3-Fucosyltransferase 4 antibody
Anti-4-Galactosyl-N-Acetylglucosaminide 3-Alpha-L-Fucosyltransferase antibody
Anti-Elam-1 Ligand Fucosyltransferase antibody
Anti-Fucosyltransferase 4 antibody
Anti-Fucosyltransferase Iv antibody
Anti-Fuc-Tiv antibody
Anti-Fuct-Iv antibody
Anti-Galactoside 3-L-Fucosyltransferase antibody
Anti-FUT4 antibody
Anti-ELFT antibody
Anti-FCT3A antibody

Information sourced from Uniprot.org

Related Products

Model Name Host Clonality Reactivity Application
STJ16103192 Anti-CD15 antibody [MMA] (STJ16103192) Mouse Monoclonal Human FC/IHC-P/IHC-F/ICC
STJ16100323 Anti-CD15 antibody [MMA] (STJ16100323) Mouse Monoclonal Human IHC-P
STJ16101810 Anti-CD15 antibody [MMA] (STJ16101810) Mouse Monoclonal Human IHC-P
STJ180038 Anti-FUT4 antibody [MMA] (STJ180038) Mouse Monoclonal Human IHC-P
STJ16103079 Anti-CD15 antibody [BRA4F1] (STJ16103079) Mouse Monoclonal Human ELISA/FC/IHC-F/IHC-P/IF

Related Products

!