Anti-CD146/MUC18/MCAM antibody [C3.19.1] {PerCP} (STJA0030396)

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STJA0030396
£231.50 - £339.50
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Host: Mouse
Applications: FC
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Mouse monoclonal antibody anti-Cell Surface Glycoprotein Muc18 is suitable for use in Flow Cytometry research applications.
Clonality : Monoclonal
Clone ID : C3.19.1
Conjugation: PerCP
Isotype: IgG2ak
Formulation: 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.
Purification: Purified
Concentration: 0.5 mg/mL
Storage Instruction: Store at 4°C for 12 months. Protect from light. Do not freeze.
Gene Symbol: MCAM
Gene ID: 4162
Uniprot ID: MUC18_HUMAN
Function Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as a surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.
Protein Name Cell Surface Glycoprotein Muc18
Cell Surface Glycoprotein P1h12
Melanoma Cell Adhesion Molecule
Melanoma-Associated Antigen A32
Melanoma-Associated Antigen Muc18
S-Endo 1 Endothelial-Associated Antigen
Cd Antigen Cd146
Database Links Reactome: R-HSA-8980692
Reactome: R-HSA-9013026
Reactome: R-HSA-9013106
Reactome: R-HSA-9013149
Reactome: R-HSA-9013404
Reactome: R-HSA-9013405
Reactome: R-HSA-9013408
Reactome: R-HSA-9013423
Reactome: R-HSA-9035034
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Cell Surface Glycoprotein Muc18 antibody
Anti-Cell Surface Glycoprotein P1h12 antibody
Anti-Melanoma Cell Adhesion Molecule antibody
Anti-Melanoma-Associated Antigen A32 antibody
Anti-Melanoma-Associated Antigen Muc18 antibody
Anti-S-Endo 1 Endothelial-Associated Antigen antibody
Anti-Cd Antigen Cd146 antibody
Anti-MCAM antibody
Anti-MUC18 antibody

Information sourced from Uniprot.org