| Host: | Rabbit |
| Applications: | FC |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Conjugation: | ABflo® 594 |
| Isotype: | IgG |
| Formulation: | PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis) , pH 7.3. |
| Purification: | Affinity purification |
| Dilution Range: | FC, 5 Mu l per 10^6 cells in 100 Mu l volume |
| Storage Instruction: | Store at 4°C for up to 1 year from the date of receipt. Do not freeze. |
| Gene Symbol: | Sdc1 |
| Gene ID: | 20969 |
| Uniprot ID: | SDC1_MOUSE |
| Immunogen: | Recombinant protein (or fragment).This information is considered to be commercially sensitive. |
| Post Translational Modifications | Shedding is enhanced by a number of factors such as heparanase, thrombin or EGF. Also by stress and wound healing. PMA-mediated shedding is inhibited by TIMP3. |
| Function | Cell surface proteoglycan that contains both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP. Able to induce its own expression in dental mesenchymal cells and also in the neighboring dental epithelial cells via an MSX1-mediated pathway. |
| Protein Name | Syndecan-1Synd1Cd Antigen Cd138 |
| Database Links | Reactome: R-MMU-1971475Reactome: -MMU-2022928Reactome: -MMU-2024096Reactome: -MMU-202733Reactome: -MMU-3000170Reactome: -MMU-449836Reactome: -MMU-975634 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinSecretedExtracellular ExosomeShedding Of The Ectodomain Produces A Soluble Form |
| Alternative Antibody Names | Anti-Syndecan-1 antibodyAnti-Synd1 antibodyAnti-Cd Antigen Cd138 antibodyAnti-Sdc1 antibodyAnti-Synd-1 antibodyAnti-Synd1 antibody |
Information sourced from Uniprot.org