| Host: | Mouse |
| Applications: | FC |
| Reactivity: | Human |
| Note: | FOR RESEARCH USE ONLY (RUO). |
| Short Description : | Mouse monoclonal antibody anti-Syndecan-1 is suitable for use in Flow Cytometry research applications. |
| Clonality : | Monoclonal |
| Clone ID : | B-A38 |
| Conjugation: | R-PE |
| Isotype: | IgG1 |
| Formulation: | PBS with 0.2% BSA, and 0.09% Sodium Azide |
| Purification: | Protein A purification |
| Dilution Range: | Please carry out application specific titration to determine the most appropriate dilution ratio. |
| Storage Instruction: | Shipped on gel ice packs. Store at 2-8C on arrival. |
| Gene Symbol: | SDC1 |
| Gene ID: | 6382 |
| Uniprot ID: | SDC1_HUMAN |
| Post Translational Modifications | Shedding is enhanced by a number of factors such as heparanase, thrombin or EGF. Also by stress and wound healing. PMA-mediated shedding is inhibited by TIMP3. |
| Function | Cell surface proteoglycan that contains both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP. Able to induce its own expression in dental mesenchymal cells and also in the neighboring dental epithelial cells via an MSX1-mediated pathway. |
| Protein Name | Syndecan-1Synd1Cd Antigen Cd138 |
| Database Links | Reactome: R-HSA-1971475Reactome: R-HSA-2022928Reactome: R-HSA-2024096Reactome: R-HSA-202733Reactome: R-HSA-3000170Reactome: R-HSA-3560783Reactome: R-HSA-3560801Reactome: R-HSA-3656237Reactome: R-HSA-3656253Reactome: R-HSA-4420332Reactome: R-HSA-449836Reactome: R-HSA-9694614Reactome: R-HSA-975634Reactome: R-HSA-9820960Reactome: R-HSA-9833110 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinSecretedExtracellular ExosomeShedding Of The Ectodomain Produces A Soluble Form |
| Alternative Antibody Names | Anti-Syndecan-1 antibodyAnti-Synd1 antibodyAnti-Cd Antigen Cd138 antibodyAnti-SDC1 antibodyAnti-SDC antibody |
Information sourced from Uniprot.org