Anti-CD125/IL5RA antibody [SAA0047] (STJA0027066)

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STJA0027066
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Covered by St John's Laboratory Guarantee

Host: Mouse
Applications: FC
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Mouse monoclonal antibody anti-Interleukin-5 Receptor Subunit Alpha is suitable for use in Flow Cytometry research applications.
Clonality : Monoclonal
Clone ID : SAA0047
Conjugation: Unconjugated
Isotype: IgG1k
Formulation: 0.01M PBS, pH 7.4.
Purification: Protein A/G purified from cell culture supernatant.
Concentration: 1 mg/ml
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks. For longer term store at-20°C for up to 12 months.
Gene Symbol: IL5RA
Gene ID: 3568
Uniprot ID: IL5RA_HUMAN
Function Cell surface receptor that plays an important role in the survival, differentiation, and chemotaxis of eosinophils. Acts by forming a heterodimeric receptor with CSF2RB subunit and subsequently binding to interleukin-5. In unstimulated conditions, interacts constitutively with JAK2. Heterodimeric receptor activation leads to JAK2 stimulation and subsequent activation of the JAK-STAT pathway.
Protein Name Interleukin-5 Receptor Subunit Alpha
Il-5 Receptor Subunit Alpha
Il-5r Subunit Alpha
Il-5r-Alpha
Il-5ra
Cdw125
Cd Antigen Cd125
Database Links Reactome: R-HSA-512988
Reactome: R-HSA-5673001
Reactome: R-HSA-912526
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Interleukin-5 Receptor Subunit Alpha antibody
Anti-Il-5 Receptor Subunit Alpha antibody
Anti-Il-5r Subunit Alpha antibody
Anti-Il-5r-Alpha antibody
Anti-Il-5ra antibody
Anti-Cdw125 antibody
Anti-Cd Antigen Cd125 antibody
Anti-IL5RA antibody
Anti-IL5R antibody

Information sourced from Uniprot.org

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