| Host: |
Mouse |
| Applications: |
IHC-P |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Mouse monoclonal antibody anti-CD11c (637-827aa) is suitable for use in Immunohistochemistry research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
ZM103 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG1/Kappa |
| Formulation: |
Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin |
| Purification: |
Affinity purified |
| Dilution Range: |
1:100‐200 |
| Storage Instruction: |
Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C. |
| Gene Symbol: |
ITGAX |
| Gene ID: |
3687 |
| Uniprot ID: |
ITAX_HUMAN |
| Immunogen Region: |
637-827aa |
| Specificity: |
Positive control: Tonsil, lymph node |
| Immunogen: |
Recombinant human ITGAX protein fragment (aa 637-827) |
| Tissue Specificity | Predominantly expressed in monocytes and granulocytes. |
| Function | Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis. |
| Protein Name | Integrin Alpha-XCd11 Antigen-Like Family Member CLeu M5Leukocyte Adhesion Glycoprotein P150 -95 Alpha ChainLeukocyte Adhesion Receptor P150 -95Cd Antigen Cd11c |
| Database Links | Reactome: R-HSA-202733Reactome: R-HSA-216083Reactome: R-HSA-3000178Reactome: R-HSA-6785807Reactome: R-HSA-6798695 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Integrin Alpha-X antibodyAnti-Cd11 Antigen-Like Family Member C antibodyAnti-Leu M5 antibodyAnti-Leukocyte Adhesion Glycoprotein P150 -95 Alpha Chain antibodyAnti-Leukocyte Adhesion Receptor P150 -95 antibodyAnti-Cd Antigen Cd11c antibodyAnti-ITGAX antibodyAnti-CD11C antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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