![Anti-CD117/c-kit antibody [YR145] (STJ16100320)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/149038/346654/STJ16100320_1__38012.1681998729.jpg?c=1 "Anti-CD117/c-kit antibody [YR145] (STJ16100320)")
![Anti-CD117/c-kit antibody [YR145] (STJ16100320)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/149038/346654/STJ16100320_1__38012.1681998729.jpg?c=1 "Anti-CD117/c-kit antibody [YR145] (STJ16100320)")
| Short Description : | Rabbit monoclonal anti-CD117/c-kit for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | IHC-P |
| Host: | Rabbit |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | YR145 |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Dilution Range: | IHC 1:25-1:100 |
| Formulation: | Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide |
| Storage Instruction: | Store at 2-8°C for up to 1-year, upon receipt. |
| Background | CD117, c-kit is a tyrosine kinase receptor found on interstitial cells of Cajal, germ cells, bone marrow stem cells, melanocytes, breast epithelium and mast cells. This receptor is found on a wide variety of tumor cells (follicular and papillary carcinoma of thyroid, adenocarcinomas from endometrium, lung, ovary, pancreas, breast; malignant melanoma, endodermal sinus tumor, and small cell carcinoma) but has been particularly useful in differentiating gastrointestinal stromal tumors from Kaposi s sarcoma, and tumors of smooth muscle origin. |
Information sourced from Uniprot.org
