| Host: | Rabbit |
| Applications: | IHC-P |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit monoclonal antibody anti-CD117 is suitable for use in Immunohistochemistry research applications. |
| Clonality : | Monoclonal |
| Clone ID : | EP10 |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Tissue culture supernatant with sodium azide |
| Concentration: | >=13 mg/L |
| Dilution Range: | IHC-P 1:200 |
| Storage Instruction: | Store at 2-8°C upon receipt. |
| Immunogen: | A synthetic peptide corresponding to residues in the C-terminus of human CD117 protein. |
| Background | The c-kit proto-oncogene encodes a transmembrane receptor with tyrosine kinase activity, c-kit (CD117) , which is closely-related to the platelet-derived growth factor receptor family. c-kit plays a role during hematopoiesis, gametogenesis and melanogenesis. The expression of CD117 antigen is of particular interest in the study of gastrointestinal stromal tumors (GIST) , small lung cell carcinomas and in melanomas. |
Information sourced from Uniprot.org