Anti-CD112/Nectin-2/PVRL2 antibody [SAA0405] {FITC} (STJA0028676)

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STJA0028676-100
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Short Description :Mouse monoclonal Nectin-2 antibody for use in ELISA and FC in human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:ELISA/FC
Host:Mouse
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :SAA0405
Isotype:IgG2ak
Conjugation:FITC
Concentration:0.5 mg/mL
Purification:Purified
Formulation:PBS pH 7.4, 50% glycerol, 0.05% proclin300
Storage Instruction:Store at 4°C for 12 months. Protect from light. Do not freeze.
Gene Symbol:NECTIN2
Gene ID:5819
Uniprot ID:NECT2_HUMAN
Function Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive. Probable cell adhesion protein. (Microbial infection) Acts as a receptor for herpes simplex virus 1 (HHV-1) mutant Rid1, herpes simplex virus 1 (HHV-2) and pseudorabies virus (PRV).
Protein Name Nectin-2
Herpes Virus Entry Mediator B
Herpesvirus Entry Mediator B
Hveb
Nectin Cell Adhesion Molecule 2
Poliovirus Receptor-Related Protein 2
Cd Antigen Cd112
Database Links Reactome: R-HSA-198933
Reactome: R-HSA-418990
Reactome: R-HSA-420597
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Nectin-2 antibody
Anti-Herpes Virus Entry Mediator B antibody
Anti-Herpesvirus Entry Mediator B antibody
Anti-Hveb antibody
Anti-Nectin Cell Adhesion Molecule 2 antibody
Anti-Poliovirus Receptor-Related Protein 2 antibody
Anti-Cd Antigen Cd112 antibody
Anti-NECTIN2 antibody
Anti-HVEB antibody
Anti-PRR2 antibody
Anti-PVRL2 antibody

Information sourced from Uniprot.org

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