Name: Anti-CD112 antibody (32-345 aa) (STJ11105181)
SKU: STJ11105181
Availability: InStock

Anti-CD112 antibody (32-345 aa) (STJ11105181)

SKU:

STJ11105181

£112.50 - £524.50

Host:	Rabbit
Applications:	WB/ELISA
Reactivity:	Human/Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality :	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3.
Purification:	Affinity purification
Concentration:	Lot specific
Dilution Range:	WB:1:1000-1:5000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	Nectin2
Gene ID:	19294
Uniprot ID:	NECT2_MOUSE
Immunogen Region:	32-345 aa
Specificity:	Recombinant fusion protein containing a sequence corresponding to amino acids 32-345 of mouse CD112. (NP_033016.3).
Immunogen Sequence:	QDVRVRVLPEVRGRLGGTVE LPCHLLPPTTERVSQVTWQR LDGTVVAAFHPSFGVDFPNS QFSKDRLSFVRARPETNADL RDATLAFRGLRVEDEGNYTC EFATFPNGTRRGVTWLRVIA QPENHAEAQEVTIGPQSVAV ARCVSTGGRPPARITWISSL GGEAKDTQEPGIQAGTVTII SRYSLVPVGRADGVKVTCRV EHESFEEPILLPVTLSVRYP PEVSISGYDDNWYLGRSEA

Tissue Specificity	Brain, spinal cord, spleen, kidney, heart and liver.
Function	Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive. Probable cell adhesion protein.
Protein Name	Nectin-2 Herpes Virus Entry Mediator B Herpesvirus Entry Mediator B Hveb Murine Herpes Virus Entry Protein B Mhveb Nectin Cell Adhesion Molecule 2 Poliovirus Receptor Homolog Poliovirus Receptor-Related Protein 2 Cd Antigen Cd112
Database Links	Reactome: R-MMU-198933 Reactome: -MMU-418990 Reactome: -MMU-420597
Cellular Localisation	Cell Membrane Single-Pass Type I Membrane Protein
Alternative Antibody Names	Anti-Nectin-2 antibody Anti-Herpes Virus Entry Mediator B antibody Anti-Herpesvirus Entry Mediator B antibody Anti-Hveb antibody Anti-Murine Herpes Virus Entry Protein B antibody Anti-Mhveb antibody Anti-Nectin Cell Adhesion Molecule 2 antibody Anti-Poliovirus Receptor Homolog antibody Anti-Poliovirus Receptor-Related Protein 2 antibody Anti-Cd Antigen Cd112 antibody Anti-Nectin2 antibody Anti-Mph antibody Anti-Pvr antibody Anti-Pvrl2 antibody Anti-Pvs antibody

Information sourced from Uniprot.org

Model	Name	Host	Clonality	Reactivity	Application
STJ195422	Anti-ZBBX antibody (295-345 aa) (STJ195422)	Rabbit	Polyclonal	Human/Mouse	WB
STJ194918	Anti-ADAT3 antibody (295-345 aa) (STJ194918)	Rabbit	Polyclonal	Human/Mouse/Rat	WB
STJ195550	Anti-WDR49 antibody (345-395 aa) (STJ195550)	Rabbit	Polyclonal	Human/Rat/Mouse	WB
STJ96346	Anti-ZNF75D antibody (296-345 aa) (STJ96346)	Rabbit	Polyclonal	Human/Rat/Mouse	WB/IHC/IF/ELISA
STJ192009	Anti-TUBA1A antibody (295-345 aa) (STJ192009)	Rabbit	Polyclonal	Human/Rat/Mouse	WB/ELISA

Anti-CD112 antibody (32-345 aa) (STJ11105181)