• C57BL/6 murine splenocytes were stained with Anti-CD103 antibody (STJA0000463) [Used at 0.2 µg/10<sup>6</sup> cells dilution] (filled gray histogram). Unstained lymphocytes (empty black histogram) were used as control.

Anti-CD103/Itgae antibody [M290] {FITC} (STJA0000463)

SKU:
STJA0000463

£118.50 - £184.50
Current Stock:
Host: Rat
Applications: FC
Reactivity: Mouse
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Short Description: Rat monoclonal antibody anti-Integrin alpha-E is suitable for use in Flow Cytometry research applications.
Clonality: Monoclonal
Clone ID: M290
Conjugation: FITC
Isotype: IgG2ak
Formulation: PBS with 0.05% Proclin300, 1% BSA
Concentration: 0.5 mg/mL
Storage Instruction: Recommend storing between 2-8°C and protecting from prolonged exposure to light. Do not freeze this product.
Gene Symbol: Itgae
Gene ID: 16407
Uniprot ID: ITAE_MOUSE
Function Integrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers. Mice expressing a null mutation of the alpha-E subunit gene exhibit a marked reduction in the numbers of intraepithelial lymphocytes in the gut and in the development of gut-associated lymphoid aggregates, supporting a specific role for this integrin in mediating retention of lymphocytes in the intestinal wall.
Protein Name Integrin Alpha-E
Integrin Alpha M290
Cd Antigen Cd103 Cleaved Into - Integrin Alpha-E Light Chain - Integrin Alpha-E Heavy Chain
Database Links Reactome: R-MMU-216083
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Integrin Alpha-E antibody
Anti-Integrin Alpha M290 antibody
Anti-Cd Antigen Cd103 Cleaved Into - Integrin Alpha-E Light Chain - Integrin Alpha-E Heavy Chain antibody
Anti-Itgae antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance