• Western blot analysis of Mouse thymus, using CD103 Rabbit polyclonal antibody (STJ11104994) at 1:900 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 30s.

Anti-CD103 antibody (191-385 aa) (STJ11104994)

SKU:
STJ11104994

£112.50 - £524.50
Current Stock:
Host: Rabbit
Applications: WB/ELISA
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: Itgae
Gene ID: 16407
Uniprot ID: ITAE_MOUSE
Immunogen Region: 191-385 aa
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 191-385 of mouse CD103. (NP_032425.2).
Immunogen Sequence: EDGTEIAIVLDGSGSIEPSD FQKAKNFISTMMRNFYEKCF ECNFALVQYGAVIQTEFDLQ ESRDINASLAKVQSIVQVKE VTKTASAMQHVLDNIFIPSR GSRKKALKVMVVLTDGDIFG DPLNLTTVINSPKMQGVVRF AIGVGDAFKNNNTYRELKLI ASDPKEAHTFKVTNYSALDG LLSKLQQHIVHMEGT
Function Integrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers. Mice expressing a null mutation of the alpha-E subunit gene exhibit a marked reduction in the numbers of intraepithelial lymphocytes in the gut and in the development of gut-associated lymphoid aggregates, supporting a specific role for this integrin in mediating retention of lymphocytes in the intestinal wall.
Protein Name Integrin Alpha-E
Integrin Alpha M290
Cd Antigen Cd103 Cleaved Into - Integrin Alpha-E Light Chain - Integrin Alpha-E Heavy Chain
Database Links Reactome: R-MMU-216083
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Integrin Alpha-E antibody
Anti-Integrin Alpha M290 antibody
Anti-Cd Antigen Cd103 Cleaved Into - Integrin Alpha-E Light Chain - Integrin Alpha-E Heavy Chain antibody
Anti-Itgae antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance