Immunohistochemistry analysis of paraffin-embedded Mouse brain using CCT8 antibody (STJ111219) at dilution of 1:100 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6. 0 before commencing with immunohistochemistry staining protocol.

Anti-CCT8 antibody (248-497) (STJ111219)

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STJ111219
£112.50 - £524.50
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Host: Rabbit
Applications: WB/IHC-P/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:1000-1:2000
IHC-P:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CCT8
Gene ID: 10694
Uniprot ID: TCPQ_HUMAN
Immunogen Region: 248-497
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 248-497 of human CCT8 (NP_001269837.1).
Immunogen Sequence: DMALHYANKYNIMLVRLNSK WDLRRLCKTVGATALPRLTP PVLEEMGHCDSVYLSEVGDT QVVVFKHEKEDGAISTIVLR GSTDNLMDDIERAVDDGVNT FKVLTRDKRLVPGGGATEIE LAKQITSYGETCPGLEQYAI KKFAEAFEAIPRALAENSGV KANEVISKLYAVHQEGNKNV GLDIEAEVPAVKDMLEAGIL DTYLGKYWAIKLATNAAVTV LRVDQIIMAKPAGGPKPPS
Function Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. The TRiC complex plays a role in the folding of actin and tubulin (Probable).
Protein Name T-Complex Protein 1 Subunit Theta
Tcp-1-Theta
Cct-Theta
Chaperonin Containing T-Complex Polypeptide 1 Subunit 8
Renal Carcinoma Antigen Ny-Ren-15
Database Links Reactome: R-HSA-389957
Reactome: R-HSA-389960
Reactome: R-HSA-390450
Reactome: R-HSA-390471
Reactome: R-HSA-5620922
Reactome: R-HSA-6798695
Reactome: R-HSA-6814122
Cellular Localisation Cytoplasm
Cytoskeleton
Microtubule Organizing Center
Centrosome
Cilium Basal Body
Alternative Antibody Names Anti-T-Complex Protein 1 Subunit Theta antibody
Anti-Tcp-1-Theta antibody
Anti-Cct-Theta antibody
Anti-Chaperonin Containing T-Complex Polypeptide 1 Subunit 8 antibody
Anti-Renal Carcinoma Antigen Ny-Ren-15 antibody
Anti-CCT8 antibody
Anti-C21orf112 antibody
Anti-CCTQ antibody
Anti-KIAA0002 antibody

Information sourced from Uniprot.org

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