| Host: |
Rabbit |
| Applications: |
WB/IHC |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CCT8 (248-497) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:1000-1:2000IHC-P 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CCT8 |
| Gene ID: |
10694 |
| Uniprot ID: |
TCPQ_HUMAN |
| Immunogen Region: |
248-497 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 248-497 of human CCT8 (NP_001269837.1). |
| Immunogen Sequence: |
DMALHYANKYNIMLVRLNSK WDLRRLCKTVGATALPRLTP PVLEEMGHCDSVYLSEVGDT QVVVFKHEKEDGAISTIVLR GSTDNLMDDIERAVDDGVNT FKVLTRDKRLVPGGGATEIE LAKQITSYGETCPGLEQYAI KKFAEAFEAIPRALAENSGV KANEVISKLYAVHQEGNKNV GLDIEAEVPAVKDMLEAGIL DTYLGKYWAIKLATNAAVTV LRVDQIIMAKPAGGPKPPS |
| Function | Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. The TRiC complex plays a role in the folding of actin and tubulin (Probable). |
| Protein Name | T-Complex Protein 1 Subunit ThetaTcp-1-ThetaCct-ThetaChaperonin Containing T-Complex Polypeptide 1 Subunit 8Renal Carcinoma Antigen Ny-Ren-15 |
| Database Links | Reactome: R-HSA-389957Reactome: R-HSA-389960Reactome: R-HSA-390450Reactome: R-HSA-390471Reactome: R-HSA-5620922Reactome: R-HSA-6798695Reactome: R-HSA-6814122 |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeCilium Basal Body |
| Alternative Antibody Names | Anti-T-Complex Protein 1 Subunit Theta antibodyAnti-Tcp-1-Theta antibodyAnti-Cct-Theta antibodyAnti-Chaperonin Containing T-Complex Polypeptide 1 Subunit 8 antibodyAnti-Renal Carcinoma Antigen Ny-Ren-15 antibodyAnti-CCT8 antibodyAnti-C21orf112 antibodyAnti-CCTQ antibodyAnti-KIAA0002 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
