Host: | Rabbit |
Applications: | WB/IHC-P/ELISA |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
Purification: | Affinity purification |
Concentration: | Lot specific |
Dilution Range: | WB:1:1000-1:2000 IHC-P:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | CCT8 |
Gene ID: | 10694 |
Uniprot ID: | TCPQ_HUMAN |
Immunogen Region: | 248-497 |
Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 248-497 of human CCT8 (NP_001269837.1). |
Immunogen Sequence: | DMALHYANKYNIMLVRLNSK WDLRRLCKTVGATALPRLTP PVLEEMGHCDSVYLSEVGDT QVVVFKHEKEDGAISTIVLR GSTDNLMDDIERAVDDGVNT FKVLTRDKRLVPGGGATEIE LAKQITSYGETCPGLEQYAI KKFAEAFEAIPRALAENSGV KANEVISKLYAVHQEGNKNV GLDIEAEVPAVKDMLEAGIL DTYLGKYWAIKLATNAAVTV LRVDQIIMAKPAGGPKPPS |
Function | Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. The TRiC complex plays a role in the folding of actin and tubulin (Probable). |
Protein Name | T-Complex Protein 1 Subunit Theta Tcp-1-Theta Cct-Theta Chaperonin Containing T-Complex Polypeptide 1 Subunit 8 Renal Carcinoma Antigen Ny-Ren-15 |
Database Links | Reactome: R-HSA-389957 Reactome: R-HSA-389960 Reactome: R-HSA-390450 Reactome: R-HSA-390471 Reactome: R-HSA-5620922 Reactome: R-HSA-6798695 Reactome: R-HSA-6814122 |
Cellular Localisation | Cytoplasm Cytoskeleton Microtubule Organizing Center Centrosome Cilium Basal Body |
Alternative Antibody Names | Anti-T-Complex Protein 1 Subunit Theta antibody Anti-Tcp-1-Theta antibody Anti-Cct-Theta antibody Anti-Chaperonin Containing T-Complex Polypeptide 1 Subunit 8 antibody Anti-Renal Carcinoma Antigen Ny-Ren-15 antibody Anti-CCT8 antibody Anti-C21orf112 antibody Anti-CCTQ antibody Anti-KIAA0002 antibody |
Information sourced from Uniprot.org