| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Copper chaperone for superoxide dismutase (225-274 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CCS |
| Gene ID: | 9973 |
| Uniprot ID: | CCS_HUMAN |
| Immunogen Region: | 225-274 aa |
| Specificity: | CCS Polyclonal Antibody detects endogenous levels of CCS protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human CCS at the amino acid range 225-274 |
| Post Translational Modifications | Ubiquitinion by XIAP/BIRC4 leads to enhancement of its chaperone activity toward its physiologic target, SOD1, rather than proteasomal degradation. XIAP/BIRC4 preferentially ubiquitinates at Lys-241. |
| Function | Delivers copper to copper zinc superoxide dismutase (SOD1). |
| Protein Name | Copper Chaperone For Superoxide DismutaseSuperoxide Dismutase Copper Chaperone |
| Database Links | Reactome: R-HSA-3299685 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Copper Chaperone For Superoxide Dismutase antibodyAnti-Superoxide Dismutase Copper Chaperone antibodyAnti-CCS antibody |
Information sourced from Uniprot.org