| Host: | Rabbit |
| Applications: | WB/IF/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-C-C chemokine receptor-like 2 (141-190 aa) is suitable for use in Western Blot, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IF 1:200-1:1000ELISA 1:20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CCRL2 |
| Gene ID: | 9034 |
| Uniprot ID: | CCRL2_HUMAN |
| Immunogen Region: | 141-190 aa |
| Specificity: | CCRL2 Polyclonal Antibody detects endogenous levels of CCRL2 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human CCRL2 at the amino acid range 141-190 |
| Function | Receptor for CCL19 and chemerin/RARRES2. Does not appear to be a signaling receptor, but may have a role in modulating chemokine-triggered immune responses by capturing and internalizing CCL19 or by presenting RARRES2 ligand to CMKLR1, a functional signaling receptors. Plays a critical role for the development of Th2 responses. |
| Protein Name | C-C Chemokine Receptor-Like 2Chemokine Receptor Ccr11Chemokine Receptor XPutative Mcp-1 Chemokine Receptor |
| Database Links | Reactome: R-HSA-380108 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-C-C Chemokine Receptor-Like 2 antibodyAnti-Chemokine Receptor Ccr11 antibodyAnti-Chemokine Receptor X antibodyAnti-Putative Mcp-1 Chemokine Receptor antibodyAnti-CCRL2 antibodyAnti-CCR11 antibodyAnti-CCR6 antibodyAnti-CKRX antibodyAnti-CRAM antibodyAnti-HCR antibody |
Information sourced from Uniprot.org