Host: |
Rabbit |
Applications: |
WB/IF |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-CCR7 (330-377) is suitable for use in Western Blot and Immunofluorescence research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:1000IF/ICC 1:50-1:200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
CCR7 |
Gene ID: |
1236 |
Uniprot ID: |
CCR7_HUMAN |
Immunogen Region: |
330-377 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 330-377 of human CCR7 (NP_001829.1). |
Immunogen Sequence: |
GVKFRNDLFKLFKDLGCLSQ EQLRQWSSCRHIRRSSMSVE AET |
Tissue Specificity | Expressed in various lymphoid tissues and activated B- and T-lymphocytes, strongly up-regulated in B-cells infected with Epstein-Barr virus and T-cells infected with herpesvirus 6 or 7. |
Function | Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions. |
Protein Name | C-C Chemokine Receptor Type 7C-C Ckr-7Cc-Ckr-7Ccr-7Blr2Cdw197Epstein-Barr Virus-Induced G-Protein Coupled Receptor 1Ebi1Ebv-Induced G-Protein Coupled Receptor 1Mip-3 Beta ReceptorCd Antigen Cd197 |
Database Links | Reactome: R-HSA-380108Reactome: R-HSA-418594 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
Alternative Antibody Names | Anti-C-C Chemokine Receptor Type 7 antibodyAnti-C-C Ckr-7 antibodyAnti-Cc-Ckr-7 antibodyAnti-Ccr-7 antibodyAnti-Blr2 antibodyAnti-Cdw197 antibodyAnti-Epstein-Barr Virus-Induced G-Protein Coupled Receptor 1 antibodyAnti-Ebi1 antibodyAnti-Ebv-Induced G-Protein Coupled Receptor 1 antibodyAnti-Mip-3 Beta Receptor antibodyAnti-Cd Antigen Cd197 antibodyAnti-CCR7 antibodyAnti-CMKBR7 antibodyAnti-EBI1 antibodyAnti-EVI1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance