• Western blot analysis of lysate from L929 cells, using CCR4 Antibody.
  • Immunohistochemical analysis of paraffin-embedded mouse-spleen, antibody was diluted at 1:100
  • Immunohistochemical analysis of paraffin-embedded mouse-spleen, antibody was diluted at 1:100
  • Western blot analysis of L929 cells using CKR-4 Polyclonal Antibody.. Secondary antibody was diluted at 1:20000

Anti-CCR4 antibody (1-50 aa) (STJ96655)

SKU:
STJ96655

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-C-C chemokine receptor type 4 (1-50 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC-P 1:100-300
ELISA 1:20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CCR4
Gene ID: 1233
Uniprot ID: CCR4_HUMAN
Immunogen Region: 1-50 aa
Specificity: CKR-4 Polyclonal Antibody detects endogenous levels of CKR-4 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the N-terminal region of human CCR4 at the amino acid range 1-50
Post Translational Modifications In natural killer cells, CCL22 binding induces phosphorylation on yet undefined Ser/Thr residues, most probably by beta-adrenergic receptor kinases 1 and 2.
Function High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival.
Protein Name C-C Chemokine Receptor Type 4
C-C Ckr-4
Cc-Ckr-4
Ccr-4
Ccr4
K5-5
Cd Antigen Cd194
Database Links Reactome: R-HSA-380108
Reactome: R-HSA-418594
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-C-C Chemokine Receptor Type 4 antibody
Anti-C-C Ckr-4 antibody
Anti-Cc-Ckr-4 antibody
Anti-Ccr-4 antibody
Anti-Ccr4 antibody
Anti-K5-5 antibody
Anti-Cd Antigen Cd194 antibody
Anti-CCR4 antibody
Anti-CMKBR4 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance