Anti-CCL3L1 antibody (24-93) (STJ22935)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CCL3L1 (24-93) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CCL3L1.CCL3L3 |
| Gene ID | 414062/6349 |
| Uniprot ID | CL3L1_HUMAN |
| Immunogen Region | 24-93 |
| Immunogen Sequence | APLAADTPTACCFSYTSRQI PQNFIADYFETSSQCSKPSV IFLTKRGRQVCADPSEEWVQ KYVSDLELSA |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 24-93 of human CCL3L1 (NP_066286.1). |
Additional Info
| Post Translational Modifications | The N-terminal processed forms LD78-beta(3-70) and LD78-beta(5-70) are produced by proteolytic cleavage after secretion from peripheral blood monocytes. The cleavage to yield LD78-beta(3-70) is probably achieved by DPP4. |
| Function | Chemotactic for lymphocytes and monocytes. Is a ligand for CCR1, CCR3 and CCR5. Is an inhibitor of HIV-1-infection. The processed form LD78-beta(3-70) shows a 20-fold to 30-fold higher chemotactic activity and is a very potent inhibitor of HIV-1-infection. LD78-beta(3-70) is also a ligand for CCR1, CCR3 and CCR5. |
| Protein Name | C-C Motif Chemokine 3-Like 1G0/G1 Switch Regulatory Protein 19-2Ld78-Beta(1-70Pat 464.2Small-Inducible Cytokine A3-Like 1Tonsillar Lymphocyte Ld78 Beta Protein Cleaved Into - Ld78-Beta(3-70 - Ld78-Beta(5-70 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-6783783 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-C-C Motif Chemokine 3-Like 1 antibodyAnti-G0/G1 Switch Regulatory Protein 19-2 antibodyAnti-Ld78-Beta(1-70 antibodyAnti-Pat 464.2 antibodyAnti-Small-Inducible Cytokine A3-Like 1 antibodyAnti-Tonsillar Lymphocyte Ld78 Beta Protein Cleaved Into - Ld78-Beta(3-70 - Ld78-Beta(5-70 antibodyAnti-CCL3L1 antibodyAnti-D17S1718 antibodyAnti-G0S19-2 antibodyAnti-SCYA3L1.CCL3L3 antibody |
Information sourced from Uniprot.org