| Host: | Rabbit |
| Applications: | IHC/IF/ELISA |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-C-C motif chemokine 3 (26-75 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | IHC 1:100-1:300ELISA 1:20000IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CCL3 |
| Gene ID: | 6348 |
| Uniprot ID: | CCL3_HUMAN |
| Immunogen Region: | 26-75 aa |
| Specificity: | MIP-1 Alpha Polyclonal Antibody detects endogenous levels of MIP-1 Alpha protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human MIP-1alpha at the amino acid range 26-75 |
| Function | Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). |
| Protein Name | C-C Motif Chemokine 3G0/G1 Switch Regulatory Protein 19-1Macrophage Inflammatory Protein 1-AlphaMip-1-AlphaPat 464.1Sis-BetaSmall-Inducible Cytokine A3Tonsillar Lymphocyte Ld78 Alpha Protein Cleaved Into - Mip-1-Alpha(4-69Ld78-Alpha(4-69 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-6783783 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-C-C Motif Chemokine 3 antibodyAnti-G0/G1 Switch Regulatory Protein 19-1 antibodyAnti-Macrophage Inflammatory Protein 1-Alpha antibodyAnti-Mip-1-Alpha antibodyAnti-Pat 464.1 antibodyAnti-Sis-Beta antibodyAnti-Small-Inducible Cytokine A3 antibodyAnti-Tonsillar Lymphocyte Ld78 Alpha Protein Cleaved Into - Mip-1-Alpha(4-69 antibodyAnti-Ld78-Alpha(4-69 antibodyAnti-CCL3 antibodyAnti-G0S19-1 antibodyAnti-MIP1A antibodyAnti-SCYA3 antibody |
Information sourced from Uniprot.org