| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Monoclonal |
| Clone ID: |
SRM |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: |
Ccl11 |
| Gene ID: |
20292 |
| Uniprot ID: |
CCL11_MOUSE |
| Immunogen Region: |
26-97 aa |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 26-97 of mouse CCL11/Eotaxin (NP_035460.1). |
| Immunogen Sequence: |
GSIPTSCCFIMTSKKIPNTL LKSYKRITNNRCTLKAIVFK TRLGKEICADPKKKWVQDAT KHLDQKLQTPKP |
| Tissue Specificity | Expressed constitutively in the thymus. Expression inducible in the lung (type I alveolar epithelial cells), intestine, heart, spleen, kidney. |
| Function | In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils (a prominent feature of allergic inflammatory reactions), but not lymphocytes, macrophages or neutrophils. Binds to CCR3. |
| Protein Name | EotaxinC-C Motif Chemokine 11Eosinophil Chemotactic ProteinSmall-Inducible Cytokine A11 |
| Database Links | Reactome: R-MMU-380108Reactome: -MMU-418594 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Eotaxin antibodyAnti-C-C Motif Chemokine 11 antibodyAnti-Eosinophil Chemotactic Protein antibodyAnti-Small-Inducible Cytokine A11 antibodyAnti-Ccl11 antibodyAnti-Scya11 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
