Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality : | Monoclonal |
Clone ID : | SRM |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3. |
Purification: | Affinity purification |
Concentration: | Lot specific |
Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Gene Symbol: | Ccl11 |
Gene ID: | 20292 |
Uniprot ID: | CCL11_MOUSE |
Immunogen Region: | 26-97 aa |
Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 26-97 of mouse CCL11/Eotaxin (NP_035460.1). |
Immunogen Sequence: | GSIPTSCCFIMTSKKIPNTL LKSYKRITNNRCTLKAIVFK TRLGKEICADPKKKWVQDAT KHLDQKLQTPKP |
Tissue Specificity | Expressed constitutively in the thymus. Expression inducible in the lung (type I alveolar epithelial cells), intestine, heart, spleen, kidney. |
Function | In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils (a prominent feature of allergic inflammatory reactions), but not lymphocytes, macrophages or neutrophils. Binds to CCR3. |
Protein Name | EotaxinC-C Motif Chemokine 11Eosinophil Chemotactic ProteinSmall-Inducible Cytokine A11 |
Database Links | Reactome: R-MMU-380108Reactome: -MMU-418594 |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-Eotaxin antibodyAnti-C-C Motif Chemokine 11 antibodyAnti-Eosinophil Chemotactic Protein antibodyAnti-Small-Inducible Cytokine A11 antibodyAnti-Ccl11 antibodyAnti-Scya11 antibody |
Information sourced from Uniprot.org