• Western blot analysis of lysates from KB cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-CCDC146 antibody (765-815 aa) (STJ193693)

SKU:
STJ193693

£48.00 - £252.00
Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Coiled-coil domain-containing protein 146 (765-815 aa) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CCDC146
Gene ID: 57639
Uniprot ID: CC146_HUMAN
Immunogen Region: 765-815 aa
Specificity: This antibody detects endogenous levels of CC146 at Human/Rat
Immunogen: Synthesized peptide derived from the human CC146 at the amino acid range 765-815
Function Essential for sperm flagellum biogenesis and male fertility.
Protein Name Coiled-Coil Domain-Containing Protein 146
Cellular Localisation Cytoplasm
Cytoskeleton
Microtubule Organizing Center
Centrosome
Centriole
Flagellum Axoneme
Cilium Basal Body
Midbody
In Sperm Cells
Was Seen Localized To Only One Centriole Identified As The Mother Centriole By Co-Staining With Cep164
In Other Experiments
Localization To Centrioles In Sperm Cells Was Not Observed
Localizes To The Sperm Connecting Piece And Flagellum During Spermiogenesis And To The Flagellum In Spermatozoa From Cauda Of The Epididymis
In Sperm Cell Flagellum
May Be Associated With Tubulin Doublets
(Microbial Infection) In Cells Infected With C
Trachomatis Incm
Recruited To The Periphery Of The Pathogen-Containing Vacuole But Recruitment Is Not Dependent On Incm
Alternative Antibody Names Anti-Coiled-Coil Domain-Containing Protein 146 antibody
Anti-CCDC146 antibody
Anti-KIAA1505 antibody

Information sourced from Uniprot.org

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