Function | Inhibits the Wnt/Wingless pathway by binding to CTNNB1/beta-catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellular proteins. Promotes adipocyte and cardiomyocyte differentiation. |
Protein Name | Protein Chibby Homolog 1Arpp-Binding ProteinCytosolic Leucine-Rich ProteinPigea-14Pkd2 Interactor - Golgi And Endoplasmic Reticulum-Associated 1 |
Database Links | Reactome: R-HSA-3769402 |
Cellular Localisation | Nucleus SpeckleCytoplasmCytoskeletonCilium Basal BodyMicrotubule Organizing CenterCentrosomeCentrioleGolgi ApparatusTrans-Golgi Network |
Alternative Antibody Names | Anti-Protein Chibby Homolog 1 antibodyAnti-Arpp-Binding Protein antibodyAnti-Cytosolic Leucine-Rich Protein antibodyAnti-Pigea-14 antibodyAnti-Pkd2 Interactor - Golgi And Endoplasmic Reticulum-Associated 1 antibodyAnti-CBY1 antibodyAnti-ARB1 antibodyAnti-C22orf2 antibodyAnti-CBY antibodyAnti-PGEA1 antibodyAnti-HRIHFB2025 antibody |
Information sourced from Uniprot.org