Western blot analysis of extracts of OVCAR-3 cells, using CBX1 antibody (STJ22919) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-CBX1 antibody (1-100) (STJ22919)

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STJ22919
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Applications:WB/ELISA
Host:Rabbit
Reactivity:Human/Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:Lot specific
Purification:Affinity purification
Dilution Range:WB:1:500-1:1000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation:PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:CBX1
Gene ID:10951
Uniprot ID:CBX1_HUMAN
Immunogen Region:1-100
Immunogen Sequence:MGKKQNKKKVEEVLEEEEEE YVVEKVLDRRVVKGKVEYLL KWKGFSDEDNTWEPEENLDC PDLIAEFLQSQKTAHETDKS EGGKRKADSDSEDKGEESKP
Specificity:A synthetic peptide corresponding to a sequence within amino acids 1-100 of human HP1 beta/CBX1 (NP_006798.1).
Tissue Specificity Expressed in all adult and embryonic tissues.
Post Translational Modifications Not phosphorylated. Ubiquitinated.
Function Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane.
Protein Name Chromobox Protein Homolog 1
Hp1hsbeta
Heterochromatin Protein 1 Homolog Beta
Hp1 Beta
Heterochromatin Protein P25
M31
Modifier 1 Protein
P25beta
Database Links Reactome: R-HSA-9609690
Cellular Localisation Nucleus
Unassociated With Chromosomes During Mitosis
Alternative Antibody Names Anti-Chromobox Protein Homolog 1 antibody
Anti-Hp1hsbeta antibody
Anti-Heterochromatin Protein 1 Homolog Beta antibody
Anti-Hp1 Beta antibody
Anti-Heterochromatin Protein P25 antibody
Anti-M31 antibody
Anti-Modifier 1 Protein antibody
Anti-P25beta antibody
Anti-CBX1 antibody
Anti-CBX antibody

Information sourced from Uniprot.org

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