| Host: | Rabbit |
| Applications: | IHC/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-CATSPER1 (300-400 aa) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Lyophilised |
| Purification: | IgG purified |
| Dilution Range: | IHC, WB. A dilution of 1: 200 to 1: 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Storage Instruction: | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: | CATSPER1 |
| Gene ID: | 117144 |
| Uniprot ID: | CTSR1_HUMAN |
| Immunogen Region: | 300-400 aa |
| Specificity: | Specific for CATSPER1. |
| Immunogen: | A synthetic peptide from aa region 300-400 of human CATSPER1 conjugated to blue carrier protein was used as the antigen. |
| Function | Pore-forming subunit of the CatSper complex, a sperm-specific voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte. |
| Protein Name | Cation Channel Sperm-Associated Protein 1Catsper1Hcatsper |
| Database Links | Reactome: R-HSA-1300642 |
| Cellular Localisation | Cell ProjectionCiliumFlagellum MembraneMulti-Pass Membrane ProteinSpecifically Located In The Principal Piece Of The Sperm Tail |
| Alternative Antibody Names | Anti-Cation Channel Sperm-Associated Protein 1 antibodyAnti-Catsper1 antibodyAnti-Hcatsper antibodyAnti-CATSPER1 antibody |
Information sourced from Uniprot.org