Anti-Caspr2/CNTNAP2 antibody (1232-1331) [S3MR] (STJ11102993)

Name: Anti-Caspr2/CNTNAP2 antibody (1232-1331) [S3MR] (STJ11102993)
SKU: STJ11102993
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⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityMonoclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ11102993

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Short Description	Rabbit monoclonal Caspr2/CNTNAP2 (1232-1331) antibody for use in WB and ELISA in mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/ELISA
Host	Rabbit
Reactivity	Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Monoclonal
Clone ID	S3MR
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:1000-1:6000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	CNTNAP2
Gene ID	26047
Uniprot ID	CNTP2_HUMAN
Immunogen Region	1232-1331
Immunogen Sequence	HLDHLDSASADFPYNPGQGQ AIRNGVNRNSAIIGGVIAVV IFTILCTLVFLIRYMFRHKG TYHTNEAKGAESAESADAAI MNNDPNFTETIDESKKEWLI
Specificity	A synthetic peptide corresponding to a sequence within amino acids 1232-1331 of human Caspr2/CNTNAP2 (Q9UHC6).

Tissue Specificity	Predominantly expressed in nervous system.
Function	Required for gap junction formation (Probable). Required, with CNTNAP1, for radial and longitudinal organization of myelinated axons. Plays a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Demarcates the juxtaparanodal region of the axo-glial junction.
Protein Name	Contactin-Associated Protein-Like 2 Cell Recognition Molecule Caspr2
Database Links
Cellular Localisation	Membrane Single-Pass Type I Membrane Protein Cell Projection Axon Cell Junction Paranodal Septate Junction Expressed In The Juxtaparadonal Region
Alternative Antibody Names	Anti-Contactin-Associated Protein-Like 2 antibody Anti-Cell Recognition Molecule Caspr2 antibody Anti-CNTNAP2 antibody Anti-CASPR2 antibody Anti-KIAA0868 antibody

Information sourced from Uniprot.org