• Western blot analysis of extracts of various cell lines, using Caspr2/CNTNAP2 antibody (STJ11102993) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Anti-Caspr2/CNTNAP2 antibody (1232-1331) [S3MR] (STJ11102993)

SKU:
STJ11102993

£146.50 - £639.50
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Host: Rabbit
Applications: WB
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-Caspr2/CNTNAP2 (1232-1331) is suitable for use in Western Blot research applications.
Clonality: Monoclonal
Clone ID: S3MR
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CNTNAP2
Gene ID: 26047
Uniprot ID: CNTP2_HUMAN
Immunogen Region: 1232-1331
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1232-1331 of human Caspr2/CNTNAP2 (Q9UHC6).
Immunogen Sequence: HLDHLDSASADFPYNPGQGQ AIRNGVNRNSAIIGGVIAVV IFTILCTLVFLIRYMFRHKG TYHTNEAKGAESAESADAAI MNNDPNFTETIDESKKEWLI
Tissue Specificity Predominantly expressed in nervous system.
Function Required for gap junction formation (Probable). Required, with CNTNAP1, for radial and longitudinal organization of myelinated axons. Plays a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Demarcates the juxtaparanodal region of the axo-glial junction.
Protein Name Contactin-Associated Protein-Like 2
Cell Recognition Molecule Caspr2
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Cell Projection
Axon
Cell Junction
Paranodal Septate Junction
Expressed In The Juxtaparadonal Region
Alternative Antibody Names Anti-Contactin-Associated Protein-Like 2 antibody
Anti-Cell Recognition Molecule Caspr2 antibody
Anti-CNTNAP2 antibody
Anti-CASPR2 antibody
Anti-KIAA0868 antibody

Information sourced from Uniprot.org

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