| Host: |
Mouse |
| Applications: |
WB |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Mouse monoclonal antibody anti-Caspase-9 is suitable for use in Western Blot research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
SM4940 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG2a |
| Formulation: |
PBS with 0.02% sodium azide, 100 Mu g/ml BSA and 50% glycerol. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB (M) 1:100-1:200 |
| Storage Instruction: |
Store at-20C for up to one year, and avoid repeated freeze-thaw cycles. |
| Gene Symbol: |
Casp9 |
| Gene ID: |
12371 |
| Uniprot ID: |
CASP9_MOUSE |
| Immunogen: |
KLH conjugated Synthetic peptide corresponding to Mouse Caspase-9 |
| Function | Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates effector caspases caspase-3 (CASP3) or caspase-7 (CASP7). Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Cleaves BIRC6 following inhibition of BIRC6-caspase binding by DIABLO/SMAC. |
| Protein Name | Caspase-9Casp-9Apoptotic Protease Mch-6Apoptotic Protease-Activating Factor 3Apaf-3Ice-Like Apoptotic Protease 6Ice-Lap6 Cleaved Into - Caspase-9 Subunit P35 - Caspase-9 Subunit P10 |
| Database Links | Reactome: R-MMU-111458Reactome: -MMU-111459Reactome: -MMU-168638Reactome: -MMU-198323Reactome: -MMU-418889Reactome: -MMU-9627069 |
| Alternative Antibody Names | Anti-Caspase-9 antibodyAnti-Casp-9 antibodyAnti-Apoptotic Protease Mch-6 antibodyAnti-Apoptotic Protease-Activating Factor 3 antibodyAnti-Apaf-3 antibodyAnti-Ice-Like Apoptotic Protease 6 antibodyAnti-Ice-Lap6 Cleaved Into - Caspase-9 Subunit P35 - Caspase-9 Subunit P10 antibodyAnti-Casp9 antibodyAnti-Mch6 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
