| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.09% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CARTPT |
| Gene ID: | 9607 |
| Uniprot ID: | CART_HUMAN |
| Immunogen Region: | 1-100 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CART (NP_004282.1). |
| Immunogen Sequence: | MESSRVRLLPLLGAALLLML PLLGTRAQEDAELQPRALDI YSAVDDASHEKELIEALQEV LKKLKSKRVPIYEKKYGQVP MCDAGEQCAVRKGARIGKLC |
| Tissue Specificity | Hypothalamus. Found in neurons of the ventrolateral part of the arcuate nucleus, in the external zone of the median eminence, and also found in terminals in the periventricular part of the paraventricular nucleus. |
| Function | Satiety factor closely associated with the actions of leptin and neuropeptide Y.this anorectic peptide inhibits both normal and starvation-induced feeding and completely blocks the feeding response induced by neuropeptide Y and regulated by leptin in the hypothalamus. It promotes neuronal development and survival in vitro. |
| Protein Name | Cocaine- And Amphetamine-Regulated Transcript Protein Cleaved Into - Cart(1-39 - Cart(42-89 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Cocaine- And Amphetamine-Regulated Transcript Protein Cleaved Into - Cart(1-39 - Cart(42-89 antibodyAnti-CARTPT antibodyAnti-CART antibody |
Information sourced from Uniprot.org