| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CAPN5 |
| Gene ID: | 726 |
| Uniprot ID: | CAN5_HUMAN |
| Immunogen Region: | 361-640 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 361-640 of human CAPN5 (NP_004046.2). |
| Immunogen Sequence: | GAWTLHEDPRQNRGGGCINH KDTFFQNPQYIFEVKKPEDE VLICIQQRPKRSTRREGKGE NLAIGFDIYKVEENRQYRMH SLQHKAASSIYINSRSVFLR TDQPEGRYVIIPTTFEPGHT GEFLLRVFTDVPSNCRELRL DEPPHTCWSSLCGYPQLVTQ VHVLGAAGLKDSPTGANSYV IIKCEGDKVRSAVQKGTSTP EYNVKGIFYRKKLSQPITVQ VWNHRVLKDEFLGQVHLKA |
| Tissue Specificity | Expressed in many tissues. Strong expression in the photoreceptor cells of the retina, with a punctate pattern of labeling over the nuclei and inner segments with less expression along the other segments and outer plexiform layer. |
| Function | Calcium-regulated non-lysosomal thiol-protease. |
| Protein Name | Calpain-5Calpain Htra-3New Calpain 3Ncl-3 |
| Database Links | Reactome: R-HSA-1474228 |
| Alternative Antibody Names | Anti-Calpain-5 antibodyAnti-Calpain Htra-3 antibodyAnti-New Calpain 3 antibodyAnti-Ncl-3 antibodyAnti-CAPN5 antibodyAnti-NCL3 antibody |
Information sourced from Uniprot.org