Anti-Calretinin antibody (Full-Length) (STJA0040707)
SPECIFICATIONS
ClonalityPolyclonal
HostChicken
ConjugationUnconjugated
IsotypeIgY
ImmunogenFull-length recombinant human protein
General Information
| Short Description | Chicken polyclonal anti-Calretinin (Full-Length) for use in ICC and WB in Bovine, Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ICC/WB |
| Host | Chicken |
| Reactivity | Bovine/Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgY |
| Conjugation | Unconjugated |
| Purification | IgY preparation |
| Dilution Range | WB 1:1000-1:5000IHC 1:1000-1:5000 |
| Formulation | Lyophilized IgY preparation, with sodium azide. |
| Storage Instruction | Spin vial briefly before opening. Reconstitute with 50 ยตL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. Store lyophilized antibody at 2-8ยฐC. After reconstitution divide into aliquots and store at-20ยฐC for long-term s |
Target Information
| Gene Symbol | CALB2 |
| Gene ID | 794 |
| Uniprot ID | CALB2_HUMAN |
| Immunogen | Full-length recombinant human protein |
| Immunogen Region | Full-Length |
| Immunogen Sequence | Human |
| Specificity | Reacts with human, cow, rat, mouse. Antibody is specific for calretinin and does not recognize closely related proteins parvalbumin and calbindin as determined by Western Blotting. |
Additional Info
| Tissue Specificity | Brain. |
| Function | Calcium-binding protein involved in calcium homeostasis and signal transduction. It plays a critical role in buffering intracellular calcium levels and modulating calcium-dependent signaling pathways. Predominantly expressed in specific neuronal populations, influences synaptic plasticity and neuronal excitability, contributing to learning and memory. During embryonic development, it facilitates neuronal differentiation and maturation. |
| Protein Name | CalretininCr29 Kda Calbindin |
| Database Links | |
| Cellular Localisation | SynapseCell ProjectionDendriteLocated In DendriolesSmall Dendrites That Makes Up A Brush Structure Found As The Terminal Specialization Of A Dendrite Of A Unipolar Brush Cell |
| Alternative Antibody Names | Anti-Calretinin antibodyAnti-Cr antibodyAnti-29 Kda Calbindin antibodyAnti-CALB2 antibodyAnti-CAB29 antibody |
Information sourced from Uniprot.org