Host: | Mouse |
Applications: | FC/IP |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Mouse monoclonal antibody anti-CD10/CALLA is suitable for use in Flow Cytometry and Immunoprecipitation research applications. |
Clonality : | Monoclonal |
Clone ID : | MEM-78 |
Conjugation: | Unconjugated |
Isotype: | IgG1 |
Formulation: | Phosphate buffered saline (PBS) solution with 15 mM sodium azide |
Concentration: | 1 mg/mL |
Dilution Range: | FC 1 µg/ml-IP |
Storage Instruction: | Store at 2-8°C upon receipt. |
Post Translational Modifications | Myristoylation is a determinant of membrane targeting. Glycosylation at Asn-628 is necessary both for surface expression and neutral endopeptidase activity. |
Function | Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Catalyzes cleavage of bradykinin, substance P and neurotensin peptides. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF) and brain natriuretic factor (BNP(1-32)). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers. |
Protein Name | Neprilysin Atriopeptidase Common Acute Lymphocytic Leukemia Antigen Calla Enkephalinase Neutral Endopeptidase 24.11 Nep Neutral Endopeptidase Skin Fibroblast Elastase Sfe Cd Antigen Cd10 |
Database Links | Reactome: R-HSA-2022377 Reactome: R-HSA-5578768 Reactome: R-HSA-6798695 |
Cellular Localisation | Cell Membrane Single-Pass Type Ii Membrane Protein |
Alternative Antibody Names | Anti-Neprilysin antibody Anti-Atriopeptidase antibody Anti-Common Acute Lymphocytic Leukemia Antigen antibody Anti-Calla antibody Anti-Enkephalinase antibody Anti-Neutral Endopeptidase 24.11 antibody Anti-Nep antibody Anti-Neutral Endopeptidase antibody Anti-Skin Fibroblast Elastase antibody Anti-Sfe antibody Anti-Cd Antigen Cd10 antibody Anti-MME antibody Anti-EPN antibody |
Information sourced from Uniprot.org