| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Calcitonin Receptor (25-148) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CALCR |
| Gene ID: |
799 |
| Uniprot ID: |
CALCR_HUMAN |
| Immunogen Region: |
25-148 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 25-148 of human CALCR (NP_001733.1). |
| Immunogen Sequence: |
AFSNQTYPTIEPKPFLYVVG RKKMMDAQYKCYDRMQQLPA YQGEGPYCNRTWDGWLCWDD TPAGVLSYQFCPDYFPDFDP SEKVTKYCDEKGVWFKHPEN NRTWSNYTMCNAFTPEKLKN AYVL |
| Function | This is a receptor for calcitonin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The calcitonin receptor is thought to couple to the heterotrimeric guanosine triphosphate-binding protein that is sensitive to cholera toxin. Isoform 2: Receptor for calcitonin but is unable to couple to G proteins and activate adenylyl cyclase. Does not undergo receptor internalization following ligand binding. |
| Protein Name | Calcitonin ReceptorCt-R |
| Database Links | Reactome: R-HSA-418555Reactome: R-HSA-419812 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Calcitonin Receptor antibodyAnti-Ct-R antibodyAnti-CALCR antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
