| Host: | Mouse |
| Applications: | IHC-P |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal Calcitonin (3-116aa) antibody for use in IHC-P in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | ZM301 |
| Conjugation: | Unconjugated |
| Isotype: | IgG2bk |
| Formulation: | Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin |
| Purification: | Affinity purified |
| Dilution Range: | 1:100-200 |
| Storage Instruction: | Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C. |
| Gene Symbol: | CALCA |
| Gene ID: | 796 |
| Uniprot ID: | CALC_HUMAN |
| Immunogen Region: | 3-116aa |
| Specificity: | Positive Control: Thyroid or medullary carcinoma |
| Immunogen: | Recombinant fragment of human Calcitonin protein (around aa 3-116) |
| Function | Calcitonin: Calcitonin is a peptide hormone that causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones. Calcitonin function is mediated by the calcitonin receptor/CALCR and the CALCR-RAMP2 (AMYR2) receptor complex. Katacalcin: Katacalcin is a potent plasma calcium-lowering peptide. |
| Protein Name | Calcitonin Cleaved Into - CalcitoninCt - KatacalcinCalcitonin Carboxyl-Terminal PeptideCcpPdn-21 |
| Database Links | Reactome: R-HSA-418555Reactome: R-HSA-419812Reactome: R-HSA-977225 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Calcitonin Cleaved Into - Calcitonin antibodyAnti-Ct - Katacalcin antibodyAnti-Calcitonin Carboxyl-Terminal Peptide antibodyAnti-Ccp antibodyAnti-Pdn-21 antibodyAnti-CALCA antibodyAnti-CALC1 antibody |
Information sourced from Uniprot.org

