Anti-Calcitonin antibody (3-116aa) [ZM301] (STJ180552)

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STJ180552
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Host: Mouse
Applications: IHC-P
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Mouse monoclonal Calcitonin (3-116aa) antibody for use in IHC-P in human samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : ZM301
Conjugation: Unconjugated
Isotype: IgG2bk
Formulation: Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin
Purification: Affinity purified
Dilution Range: 1:100-200
Storage Instruction: Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C.
Gene Symbol: CALCA
Gene ID: 796
Uniprot ID: CALC_HUMAN
Immunogen Region: 3-116aa
Specificity: Positive Control: Thyroid or medullary carcinoma
Immunogen: Recombinant fragment of human Calcitonin protein (around aa 3-116)
Function Calcitonin: Calcitonin is a peptide hormone that causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones. Calcitonin function is mediated by the calcitonin receptor/CALCR and the CALCR-RAMP2 (AMYR2) receptor complex. Katacalcin: Katacalcin is a potent plasma calcium-lowering peptide.
Protein Name Calcitonin Cleaved Into - Calcitonin
Ct - Katacalcin
Calcitonin Carboxyl-Terminal Peptide
Ccp
Pdn-21
Database Links Reactome: R-HSA-418555
Reactome: R-HSA-419812
Reactome: R-HSA-977225
Cellular Localisation Secreted
Alternative Antibody Names Anti-Calcitonin Cleaved Into - Calcitonin antibody
Anti-Ct - Katacalcin antibody
Anti-Calcitonin Carboxyl-Terminal Peptide antibody
Anti-Ccp antibody
Anti-Pdn-21 antibody
Anti-CALCA antibody
Anti-CALC1 antibody

Information sourced from Uniprot.org