| Host: | Rabbit |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CALB2 |
| Gene ID: | 794 |
| Uniprot ID: | CALB2_HUMAN |
| Immunogen Region: | 1-271 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-271 of human Calretinin (NP_001731.2). |
| Immunogen Sequence: | MAGPQQQPPYLHLAELTASQ FLEIWKHFDADGNGYIEGKE LENFFQELEKARKGSGMMSK SDNFGEKMKEFMQKYDKNSD GKIEMAELAQILPTEENFLL CFRQHVGSSAEFMEAWRKYD TDRSGYIEANELKGFLSDLL KKANRPYDEPKLQEYTQTIL RMFDLNGDGKLGLSEMSRLL PVQENFLLKFQGMKLTSEEF NAIFTFYDKDRSGYIDEHEL DALLKDLYEKNKKEMNIQQ |
| Tissue Specificity | Brain. |
| Function | Calcium-binding protein involved in calcium homeostasis and signal transduction. It plays a critical role in buffering intracellular calcium levels and modulating calcium-dependent signaling pathways. Predominantly expressed in specific neuronal populations, influences synaptic plasticity and neuronal excitability, contributing to learning and memory. During embryonic development, it facilitates neuronal differentiation and maturation. |
| Protein Name | CalretininCr29 Kda Calbindin |
| Database Links | |
| Cellular Localisation | SynapseCell ProjectionDendriteLocated In DendriolesSmall Dendrites That Makes Up A Brush Structure Found As The Terminal Specialization Of A Dendrite Of A Unipolar Brush Cell |
| Alternative Antibody Names | Anti-Calretinin antibodyAnti-Cr antibodyAnti-29 Kda Calbindin antibodyAnti-CALB2 antibodyAnti-CAB29 antibody |
Information sourced from Uniprot.org
