Anti-CADM3 antibody (25-330) (STJ26947)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CADM3 (25-330) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CADM3 |
| Gene ID | 57863 |
| Uniprot ID | CADM3_HUMAN |
| Immunogen Region | 25-330 |
| Immunogen Sequence | NLSQDDSQPWTSDETVVAGG TVVLKCQVKDHEDSSLQWSN PAQQTLYFGEKRALRDNRIQ LVTSTPHELSISISNVALAD EGEYTCSIFTMPVRTAKSLV TVLGIPQKPIITGYKSSLRE KDTATLNCQSSGSKPAARLT WRKGDQELHGEPTRIQEDPN GKTFTVSSSVTFQVTREDDG ASIVCSVNHESLKGADRSTS QRIEVLYTPTAMIRPDPPHP REGQKLLLHCEGRGNPVPQ |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 25-330 of human CADM3 (NP_001120645.1). |
Additional Info
| Tissue Specificity | Isoform 1 is expressed mainly in adult and fetal brain. Isoform 2 is highly expressed in adult brain and weakly expressed in placenta. In brain, Isoform 2 is highly expressed in cerebellum. |
| Function | Involved in cell-cell adhesion. Has both calcium-independent homophilic cell-cell adhesion activity and calcium-independent heterophilic cell-cell adhesion activity with IGSF4, NECTIN1 and NECTIN3. Interaction with EPB41L1 may regulate structure or function of cell-cell junctions. |
| Protein Name | Cell Adhesion Molecule 3Brain Immunoglobulin ReceptorImmunoglobulin Superfamily Member 4bIgsf4bNectin-Like Protein 1Necl-1Synaptic Cell Adhesion Molecule 3Syncam3Tslc1-Like Protein 1Tsll1 |
| Database Links | Reactome: R-HSA-418990Reactome: R-HSA-420597 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinCell Junction |
| Alternative Antibody Names | Anti-Cell Adhesion Molecule 3 antibodyAnti-Brain Immunoglobulin Receptor antibodyAnti-Immunoglobulin Superfamily Member 4b antibodyAnti-Igsf4b antibodyAnti-Nectin-Like Protein 1 antibodyAnti-Necl-1 antibodyAnti-Synaptic Cell Adhesion Molecule 3 antibodyAnti-Syncam3 antibodyAnti-Tslc1-Like Protein 1 antibodyAnti-Tsll1 antibodyAnti-CADM3 antibodyAnti-IGSF4B antibodyAnti-NECL1 antibodyAnti-SYNCAM3 antibodyAnti-TSLL1 antibodyAnti-UNQ225 antibodyAnti-PRO258 antibody |
Information sourced from Uniprot.org