• Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using CAD Antibody. The picture on the right is blocked with the synthesized peptide.

Anti-CAD antibody (422-471 aa) (STJ91958)

SKU:
STJ91958

Current Stock:
Host: Rabbit
Applications: IHC/IF/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-CAD protein (422-471 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC 1:100-1:300
ELISA 1:20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CAD
Gene ID: 790
Uniprot ID: PYR1_HUMAN
Immunogen Region: 422-471 aa
Specificity: CAD Polyclonal Antibody detects endogenous levels of CAD protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human CAD at the amino acid range 422-471
Function This protein is a 'fusion' protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase).
Protein Name Cad Protein Includes - Glutamine-Dependent Carbamoyl-Phosphate Synthase - Aspartate Carbamoyltransferase - Dihydroorotase
Database Links Reactome: R-HSA-500753
Cellular Localisation Cytoplasm
Nucleus
Cytosolic And Unphosphorylated In Resting Cells
Translocates To The Nucleus In Response To Egf Stimulation
Nuclear Import Promotes Optimal Cell Growth
Alternative Antibody Names Anti-Cad Protein Includes - Glutamine-Dependent Carbamoyl-Phosphate Synthase - Aspartate Carbamoyltransferase - Dihydroorotase antibody
Anti-CAD antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance