Host: | Mouse |
Applications: | WB/IHC/IF/ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Mouse monoclonal antibody anti-Calcyclin-binding protein is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality : | Monoclonal |
Clone ID : | 7D11 |
Conjugation: | Unconjugated |
Isotype: | IgG1 |
Formulation: | Liquid in PBS containing 0.03% Sodium Azide. |
Purification: | Affinity purification |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-1:2000IHC 1:200-1:1000ELISA 1:10000IF 1:50-200 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | CACYBP |
Gene ID: | 27101 |
Uniprot ID: | CYBP_HUMAN |
Specificity: | Calcyclin Monoclonal Antibody detects endogenous levels of Calcyclin protein. |
Immunogen: | Purified recombinant fragment of Calcyclin expressed in E. Coli. |
Function | May be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins. Probably serves as a molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1). |
Protein Name | Calcyclin-Binding ProteinCacybpHcacybpS100a6-Binding ProteinSiah-Interacting Protein |
Cellular Localisation | NucleusCytoplasmCytoplasmic At Low Calcium ConcentrationsIn Neuroblastoma CellsAfter A Retinoic Acid (Ra) Induction And Calcium IncreaseIt Localizes In Both The Nucleus And CytoplasmThe Nuclear Fraction May Be Phosphorylated |
Alternative Antibody Names | Anti-Calcyclin-Binding Protein antibodyAnti-Cacybp antibodyAnti-Hcacybp antibodyAnti-S100a6-Binding Protein antibodyAnti-Siah-Interacting Protein antibodyAnti-CACYBP antibodyAnti-S100A6BP antibodyAnti-SIP antibodyAnti-PNAS-107 antibody |
Information sourced from Uniprot.org