Western blot analysis of 1) Human Brain Tissue, 2) Mouse Brain Tissue, 3) Rat Brain Tissue using CACNG2 Polyclonal Antibody. Secondary antibody (STJ99666) was diluted at 1:20000

Anti-CACNG2 antibody (58-108 aa) (STJ197422)

SKU:
STJ197422
£48.00 - £252.00
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Host: Rabbit
Applications: WB/IHC/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Voltage-dependent calcium channel gamma-2 subunit (58-108 aa) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS pH7.4, 0.5% BSA, 0.02% Sodium Azide and 50% Glycerol.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range: WB 1:1000-2000
IHC 1:200-500
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CACNG2
Gene ID: 10369
Uniprot ID: CCG2_HUMAN
Immunogen Region: 58-108 aa
Specificity: The antibody detects endogenous CACNG2 protein.
Immunogen: Synthetic peptide derived from CACNG2 at the amino acid range 58-108
Post Translational Modifications Phosphorylation of Thr-321 impairs interaction with DLG1 and DLG4.
Function Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.
Protein Name Voltage-Dependent Calcium Channel Gamma-2 Subunit
Neuronal Voltage-Gated Calcium Channel Gamma-2 Subunit
Transmembrane Ampar Regulatory Protein Gamma-2
Tarp Gamma-2
Database Links Reactome: R-HSA-112308
Reactome: R-HSA-399719
Reactome: R-HSA-5682910
Cellular Localisation Membrane
Multi-Pass Membrane Protein
Synapse
Synaptosome
Alternative Antibody Names Anti-Voltage-Dependent Calcium Channel Gamma-2 Subunit antibody
Anti-Neuronal Voltage-Gated Calcium Channel Gamma-2 Subunit antibody
Anti-Transmembrane Ampar Regulatory Protein Gamma-2 antibody
Anti-Tarp Gamma-2 antibody
Anti-CACNG2 antibody

Information sourced from Uniprot.org

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