| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human/Mouse/Rat/Dog |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-CACNB4 (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:4000.WB: Approx 55-60kDa band observed in Human Bone Marrow lysates (calculated MW of 54.7kDa according to NP_001005747.1 and 58.2kDa according to NP_000717.2). Recommended concentration: 0.2-0. |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | CACNB4 |
| Gene ID: | 785 |
| Uniprot ID: | CACB4_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_001005747.1; NP_000717.2; NP_001005746.1 |
| Specificity: | This antibody is expected to recognise all three reported isoforms (NP_001005747.1; NP_000717.2; NP_001005746.1). |
| Immunogen Sequence: | DYPDSYQDTYKPH |
| Function | The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting. |
| Protein Name | Voltage-Dependent L-Type Calcium Channel Subunit Beta-4Cab4Calcium Channel Voltage-Dependent Subunit Beta 4 |
| Database Links | Reactome: R-HSA-112308Reactome: R-HSA-419037 |
| Alternative Antibody Names | Anti-Voltage-Dependent L-Type Calcium Channel Subunit Beta-4 antibodyAnti-Cab4 antibodyAnti-Calcium Channel Voltage-Dependent Subunit Beta 4 antibodyAnti-CACNB4 antibodyAnti-CACNLB4 antibody |
Information sourced from Uniprot.org