| Host: | Rabbit |
| Applications: | IHC/WB |
| Reactivity: | Mouse/Rat/Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-CACNB1 (N-Term) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Lyophilised |
| Purification: | IgG purified |
| Dilution Range: | IHC, WB. A concentration of 10-50 µg/ml is recommended. The optimal concentration should be determined by the end user. Not tested in other applications. |
| Storage Instruction: | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: | Cacnb1 |
| Gene ID: | 12295 |
| Uniprot ID: | CACB1_MOUSE |
| Immunogen Region: | N-Term |
| Specificity: | Specific for CACNB1. |
| Immunogen: | A synthetic peptide from the n-terminal region of mouse CACNB1 (CAB1) conjugated to an immunogenic carrier protein was used as the immunogen. The antigen is shares 98% identity with rat and human sequences. |
| Function | Regulatory subunit of L-type calcium channels. Regulates the activity of L-type calcium channels that contain CACNA1A as pore-forming subunit. Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit and increases the presence of the channel complex at the cell membrane. Required for functional expression L-type calcium channels that contain CACNA1D as pore-forming subunit. Regulates the activity of L-type calcium channels that contain CACNA1B as pore-forming subunit. |
| Protein Name | Voltage-Dependent L-Type Calcium Channel Subunit Beta-1Cab1Calcium Channel Voltage-Dependent Subunit Beta 1 |
| Database Links | Reactome: R-MMU-112308Reactome: -MMU-5576892Reactome: -MMU-5576893 |
| Cellular Localisation | Cell MembraneSarcolemmaPeripheral Membrane ProteinCytoplasmic Side |
| Alternative Antibody Names | Anti-Voltage-Dependent L-Type Calcium Channel Subunit Beta-1 antibodyAnti-Cab1 antibodyAnti-Calcium Channel Voltage-Dependent Subunit Beta 1 antibodyAnti-Cacnb1 antibodyAnti-Cacnlb1 antibody |
Information sourced from Uniprot.org
