Anti-CACNA2D1 antibody (Internal) (STJ71200)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-CACNA2D1 (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:16000.WB: Approx 140kDa band observed in Human Brain (Cerebellum) lysates (calculated MW of 123kDa according to NP_000713.2). Recommended concentration: 0.03-0.1µg/ml. Customer found it not suit |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | CACNA2D1 |
| Gene ID | 781 |
| Uniprot ID | CA2D1_HUMAN |
| Accession Number | NP_000713.2 |
| Immunogen Region | Internal |
| Immunogen Sequence | QEIFNKYNKDKKVR |
Additional Info
| Post Translational Modifications | Proteolytically processed into subunits alpha-2-1 and delta-1 that are disulfide-linked. |
| Function | The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. Plays an important role in excitation-contraction coupling. |
| Protein Name | Voltage-Dependent Calcium Channel Subunit Alpha-2/Delta-1Voltage-Gated Calcium Channel Subunit Alpha-2/Delta-1 Cleaved Into - Voltage-Dependent Calcium Channel Subunit Alpha-2-1 - Voltage-Dependent Calcium Channel Subunit Delta-1 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinCell Membrane |
| Alternative Antibody Names | Anti-Voltage-Dependent Calcium Channel Subunit Alpha-2/Delta-1 antibodyAnti-Voltage-Gated Calcium Channel Subunit Alpha-2/Delta-1 Cleaved Into - Voltage-Dependent Calcium Channel Subunit Alpha-2-1 - Voltage-Dependent Calcium Channel Subunit Delta-1 antibodyAnti-CACNA2D1 antibodyAnti-CACNL2A antibodyAnti-CCHL2A antibodyAnti-MHS3 antibody |
Information sourced from Uniprot.org