Anti-CA3 antibody (1-260) (STJ115434)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CA3 (1-260) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CA3 |
| Gene ID | 761 |
| Uniprot ID | CAH3_HUMAN |
| Immunogen Region | 1-260 |
| Immunogen Sequence | MAKEWGYASHNGPDHWHELF PNAKGENQSPVELHTKDIRH DPSLQPWSVSYDGGSAKTIL NNGKTCRVVFDDTYDRSMLR GGPLPGPYRLRQFHLHWGSS DDHGSEHTVDGVKYAAELHL VHWNPKYNTFKEALKQRDGI AVIGIFLKIGHENGEFQIFL DALDKIKTKGKEAPFTKFDP SCLFPACRDYWTYQGSFTTP PCEECIVWLLLKEPMTVSSD QMAKLRSLLSSAENEPPVP |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human CA3 (NP_005172.1). |
Additional Info
| Tissue Specificity | Muscle specific. |
| Post Translational Modifications | S-thiolated both by thiol-disulfide exchange with glutathione disulfide and by oxyradical-initiated S-thiolation with reduced glutathione. S-glutathionylated in hepatocytes under oxidative stress. |
| Function | Reversible hydration of carbon dioxide. |
| Protein Name | Carbonic Anhydrase 3Carbonate Dehydratase IiiCarbonic Anhydrase IiiCa-Iii |
| Database Links | Reactome: R-HSA-1475029 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Carbonic Anhydrase 3 antibodyAnti-Carbonate Dehydratase Iii antibodyAnti-Carbonic Anhydrase Iii antibodyAnti-Ca-Iii antibodyAnti-CA3 antibody |
Information sourced from Uniprot.org