| Short Description : | Mouse monoclonal anti-CA12 for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | IHC-P |
| Host: | Mouse |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | ZN121 |
| Isotype: | IgG2a |
| Conjugation: | Unconjugated |
| Concentration: | 0.5-1.0 mg/mL |
| Purification: | Affinity Chromatography |
| Dilution Range: | IHC 1:50-1:100 |
| Formulation: | PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Storage Instruction: | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Gene Symbol: | CA12 |
| Gene ID: | 771 |
| Uniprot ID: | CAH12_HUMAN |
| Immunogen: | Full length human recombinant protein of human CA12 (NP_001209) produced in HEK293T cell. |
| Tissue Specificity | Highly expressed in colon, kidney, prostate, intestine and activated lymphocytes. Expressed at much higher levels in the renal cell cancers than in surrounding normal kidney tissue. Moderately expressed in pancreas, ovary and testis. Expressed in sweat glands and bronchiolar epithelium. |
| Function | Reversible hydration of carbon dioxide. |
| Protein Name | Carbonic Anhydrase 12Carbonate Dehydratase XiiCarbonic Anhydrase XiiCa-XiiTumor Antigen Hom-Rcc-3.1.3 |
| Database Links | Reactome: R-HSA-1475029 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinCell Membrane |
| Alternative Antibody Names | Anti-Carbonic Anhydrase 12 antibodyAnti-Carbonate Dehydratase Xii antibodyAnti-Carbonic Anhydrase Xii antibodyAnti-Ca-Xii antibodyAnti-Tumor Antigen Hom-Rcc-3.1.3 antibodyAnti-CA12 antibody |
Information sourced from Uniprot.org
