| Host: | Goat |
| Applications: | Pep-ELISA |
| Reactivity: | Human/Dog |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-C7orf50 (Internal) is suitable for use in ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:32000. WB: Preliminary experiments gave an approx 100kDa band in Human Duodenum lysates after 1µg/ml antibody staining. Please note that currently we cannot find an explanation in the literature |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | C7orf50 |
| Gene ID: | 84310 |
| Uniprot ID: | CHOLN_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_115726.1 |
| Specificity: | Reported variants represent identical protein: NP_001127867.1, NP_001127868.1, NP_115726.1 |
| Immunogen Sequence: | EGLQGRARELTVQK |
| Function | Hormone secreted from the intestine in response to cholesterol, where it acts to inhibit cholesterol synthesis in the liver and VLDL secretion,leading to a reduction in circulating cholesterol levels. Acts through binding to its receptor, GPR146. |
| Protein Name | Protein Cholesin |
| Cellular Localisation | Secreted Secreted Via Exosomes Secretion Is Induced By Feeding And Cholesterol Absorption |
| Alternative Antibody Names | Anti-Protein Cholesin antibody Anti-C7orf50 antibody Anti-FP15621 antibody |
Information sourced from Uniprot.org