Host: |
Rabbit |
Applications: |
WB/ELISA |
Reactivity: |
Human/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
Purification: |
Affinity purification |
Concentration: |
Lot specific |
Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
C7orf50 |
Gene ID: |
84310 |
Uniprot ID: |
CHOLN_HUMAN |
Immunogen Region: |
1-194 |
Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-194 of human C7orf50 (NP_115726.1). |
Immunogen Sequence: |
MAKQKRKVPEVTEKKNKKLK KASAEGPLLGPEAAPSGEGA GSKGEAVLRPGLDAEPELSP EEQRVLERKLKKERKKEERQ RLREAGLVAQHPPARRSGAE LALDYLCRWAQKHKNWRFQK TRQTWLLLHMYDSDKVPDEH FSTLLAYLEGLQGRARELTV QKAEALMRELDEEGSDPPLP GRAQRIRQVLQLLS |
Tissue Specificity | Secreted from the instestine, secretion is induced by feeding and cholesterol absorption. |
Function | Hormone secreted from the intestine in response to cholesterol, where it acts to inhibit cholesterol synthesis in the liver and VLDL secretion,leading to a reduction in circulating cholesterol levels. Acts through binding to its receptor, GPR146. |
Protein Name | Protein Cholesin |
Cellular Localisation | SecretedSecreted Via ExosomesSecretion Is Induced By Feeding And Cholesterol Absorption |
Alternative Antibody Names | Anti-Protein Cholesin antibodyAnti-C7orf50 antibodyAnti-FP15621 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance